Correlation of HAMP gene polymorphisms and expression with the susceptibility and length of hospital stays in Taiwanese children with Kawasaki disease.

@article{Huang2017CorrelationOH,
  title={Correlation of HAMP gene polymorphisms and expression with the susceptibility and length of hospital stays in Taiwanese children with Kawasaki disease.},
  author={Ying-Hsien Huang and Kuender D. Yang and Yao Wen Hsu and Hsing-Fang Lu and Henry Sung-Ching Wong and Hong-Ren Yu and Hsing-Chun Kuo and Fu-Chen Huang and Mathew Lo and Kai-Sheng Hsieh and Su-fen Chen and Wei-Chiao Chang and Ho-Chang Kuo},
  journal={Oncotarget},
  year={2017},
  volume={8 31},
  pages={
          51859-51868
        }
}
Kawasaki disease (KD) is a form of systemic vasculitis. Regarding its pathogenesis, HAMP gene encoding hepcidin, which is significant for iron metabolism, has a vital function. In this study, we recruited a total of 381 KD patients for genotyping. Data from 997 subjects (500 subjects from cohort 1; 497 subjects from cohort 2) were used for analysis. Using TaqMan allelic discrimination, we determined five tag SNPs (rs916145, rs10421768, rs3817623, rs7251432, and rs2293689). Treatment outcome… CONTINUE READING
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