Correlation of EGFR mutation and histological subtype according to the IASLC/ATS/ERS classification of lung adenocarcinoma.

@article{Chen2014CorrelationOE,
  title={Correlation of EGFR mutation and histological subtype according to the IASLC/ATS/ERS classification of lung adenocarcinoma.},
  author={Zhen Qian Chen and Xiaoyan Liu and Jing Zhao and Hanjin Yang and Xiaodong Teng},
  journal={International journal of clinical and experimental pathology},
  year={2014},
  volume={7 11},
  pages={8039-45}
}
OBJECTIVE To evaluate the correlation of EGFR mutation and histological subtypes of lung adenocarcinoma based on the IASLC/ATS/ERS classification. METHODS EGFR exons 18-21 of 206 resected lung adenocarcinoma specimens were analyzed with pyrosequecing, then the differences between histological subtypes and EGFR mutation were compared. RESULTS EGFR mutation was detected in 123 specmens, most of which were papillary and acinar predominant adenocarcinoma. EGFR mutation rate of the specimens… CONTINUE READING