Correlation of DRD2 mRNA expression levels with deficit syndrome severity in chronic schizophrenia patients receiving clozapine treatment

@inproceedings{Liu2017CorrelationOD,
  title={Correlation of DRD2 mRNA expression levels with deficit syndrome severity in chronic schizophrenia patients receiving clozapine treatment},
  author={Liang Liu and Yin Luo and Guofu Zhang and Chunhui Jin and Zhenhe Zhou and Zaohuo Cheng and Guozhen Yuan},
  booktitle={Oncotarget},
  year={2017}
}
Schizophrenia is a complex, severe, chronic psychiatric disorder, and the associated deficit syndrome is widely regarded as an important clinical aspect of schizophrenia. This study analyzed the relationship of deficit syndrome severity with the mRNA levels of members of signaling pathways that associate with the pathophysiology of schizophrenia, including the dopamine D2 receptor (DRD2), protein kinase B (AKT1), and phosphoinositide-3 kinase (PI3KCB), in peripheral blood leukocytes (PBLs) of… CONTINUE READING
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