Correlation of DNA exonic regions with protein structural units in haemoglobin

@article{Go1981CorrelationOD,
  title={Correlation of DNA exonic regions with protein structural units in haemoglobin},
  author={Mitiko Go},
  journal={Nature},
  year={1981},
  volume={291},
  pages={90-92}
}
  • M. Go
  • Published 7 May 1981
  • Biology
  • Nature
The discovery of intervening sequences (introns) in DNA led Gilbert and Tonegawa1,2 to suggest that a new protein could have been produced by bringing together certain segments of pre-existing ones. However, Blake3 argued that if DNA was so organized that coding sequences (exons) correspond to structural as well as functional units of proteins, then combinations would be much more likely to yield a stable globular conformation through being ‘sums of parts’. In immunoglobulin heavy chain, four… 

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...

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