Correlation between virulence of Candida albicans mutants in mice and Galleria mellonella larvae.

@article{Brennan2002CorrelationBV,
  title={Correlation between virulence of Candida albicans mutants in mice and Galleria mellonella larvae.},
  author={Marc Brennan and David Y. Thomas and Malcolm Whiteway and Kevin Kavanagh},
  journal={FEMS immunology and medical microbiology},
  year={2002},
  volume={34 2},
  pages={153-7}
}
Candida albicans is a dimorphic human pathogen in which the yeast to hyphal switch may be an important factor in virulence in mammals. This pathogen has recently been shown to also kill insects such as the Greater Wax Moth Galleria mellonella when injected into the haemocoel of the insect larvae. We have investigated the effect of previously characterised C. albicans mutations that influence the yeast to hyphal transition on virulence in G. mellonella larvae. There is a good correlation between… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
106 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 106 extracted citations

Similar Papers

Loading similar papers…