Correlation between the extent of platelet activation in platelet concentrates and in vitro and in vivo parameters.

@article{DijkstraTiekstra2004CorrelationBT,
  title={Correlation between the extent of platelet activation in platelet concentrates and in vitro and in vivo parameters.},
  author={Margriet J Dijkstra-Tiekstra and Ruby N I Pietersz and Peter C. Huijgens},
  journal={Vox sanguinis},
  year={2004},
  volume={87 4},
  pages={257-63}
}
BACKGROUND AND OBJECTIVES Platelet activation, which is necessary to stop bleeding, also occurs in vitro during the storage of platelet concentrates (PCs). However, it is unknown whether in vitro-activated platelets are able to reduce blood loss in the patient. We studied correlations between platelet activation in PCs and in vitro parameters (pH, platelet count, swirling effect, storage time). In addition, we studied the correlation between platelet activation and in vivo parameters [the… CONTINUE READING

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