Correlation between resistance profile and immunosuppression in heavily treated HIV-1 infected Romanian patients.

@article{Manolescu2011CorrelationBR,
  title={Correlation between resistance profile and immunosuppression in heavily treated HIV-1 infected Romanian patients.},
  author={Loredana Sabina Cornelia Manolescu and Aura Temereanca and Carmen C Diaconu and Simona Maria Ruţă},
  journal={Romanian biotechnological letters},
  year={2011},
  volume={16 4},
  pages={
          6439-6449
        }
}
BACKGROUND AND OBJECTIVE: As available data on HIV-1 strains from Romania indicate the prevalence of a particular subtype- F, not found in other European countries, we aimed at investigating the impact on drug susceptibility of mutations associated with drug resistance and their correlation with the virological and immune response to therapy. METHODS: 38 long term survivors, HIV-1 parenterally infected in childhood, with repeated virological failures, were genotyped for drug resistance and… CONTINUE READING

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