Correlation between quantitative imaging and behavior in unilaterally 6-OHDA-lesioned rats.

@article{Inaji2005CorrelationBQ,
  title={Correlation between quantitative imaging and behavior in unilaterally 6-OHDA-lesioned rats.},
  author={Motoki Inaji and Takashi Okauchi and Kiyoshi Ando and J. S. Maeda and Yuji Nagai and Takahito Yoshizaki and Hideyuki Okano and T Nariai and Kikuo Ohno and Shigeru Obayashi and Makoto Higuchi and Tetsuya Suhara},
  journal={Brain research},
  year={2005},
  volume={1064 1-2},
  pages={136-45}
}
We evaluated correlation between neurochemical and functional alterations of the nigrostriatal dopaminergic system in rat brains lesioned with 6-hydroxydopamine (6-OHDA), that model hemi-Parkinson's disease (PD), by using three different quantitative in vivo and in vitro methods. Rats unilaterally lesioned with different doses of 6-OHDA underwent two types of in vivo experiments: (1) a rotational behavioral study with methamphetamine (MAP) or apomorphine (APO); and (2) a positron emission… CONTINUE READING
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