Correlation between protein 4.1a/4.1b ratio and erythrocyte life span.

  title={Correlation between protein 4.1a/4.1b ratio and erythrocyte life span.},
  author={Michiko Inaba and Yoshimitsu Maede},
  journal={Biochimica et biophysica acta},
  volume={944 2},
Erythrocyte membranes from various healthy mammals contained a doublet of protein 4.1a and 4.1b, which appeared to differ by 2-3 kDa on sodium dodecyl sulfate polyacrylamide gel electrophoresis. The ratio of protein 4.1a/4.1b showed much variety among animal species, and the 4.1a/4.1b ratio correlated to the mean erythrocyte life span, that is, the mean cell age in circulating blood. We also found that the 4.1b is the predominant form in the immature erythroid cells such as reticulocytes and… CONTINUE READING


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