Correlation between prefrontal-striatal pathway impairment and cognitive impairment in patients with leukoaraiosis

Abstract

Our study aimed to investigate the changes of white matter microstructure of cortico-subcortical pathways using diffusion tensor imaging (DTI), and to explore the relationship between abnormal parameters of DTI and cognitive function underlying in patients with leukoaraiosis (LA).A total of 42 patients with LA and 42 age- and sex-matched healthy controls… (More)
DOI: 10.1097/MD.0000000000006703

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