Corpus ID: 23176231

Correlation between phosphatidylinositol labeling and contraction in rabbit aorta: effect of alpha-1 adrenergic activation.

@article{VillalobosMolina1982CorrelationBP,
  title={Correlation between phosphatidylinositol labeling and contraction in rabbit aorta: effect of alpha-1 adrenergic activation.},
  author={R. Villalobos-Molina and M. Uc and E. Hong and J. Garc{\'i}a-S{\'a}inz},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={1982},
  volume={222 1},
  pages={
          258-61
        }
}
Activation of rabbit aortic strips with alpha adrenergic agonists increased the labeling (with [32P]Pi) of phosphatidylinositol (PI) and phosphatidic acid and contracted the vascular preparations in dose-related fashion. Epinephrine, norepinephrine and methoxamine produced maximal effects, whereas clonidine behaved as partial agonist and B-HT 933 (2-amino-6-ethyl-4,5,7,8-tetrahydro-6H-oxazole-[5,4-d] azepin dihydrochloride) was almost without activity in the two experimental models used… Expand
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