Corpus ID: 203649582

Correlation between myostatin and obesity or insulin resistance of patients with polycystic ovary syndrome

@inproceedings{Lu2015CorrelationBM,
  title={Correlation between myostatin and obesity or insulin resistance of patients with polycystic ovary syndrome},
  author={Zhai Lu and Hua Chen and Man-ling Chen and Song-hua Jin and Yueping Li},
  year={2015}
}

Tables from this paper

Use of Myostatin levels in early detection of PCOS and evaluation of the mechanism
DOI: 10.4328/ACAM.20257 Received: 2020-06-24 Accepted: 2020-07-25 Published Online: 2020-08-06 Printed: 2021-03-01 Ann Clin Anal Med 2021;12(3):264-268 Corresponding Author: Deniz Simsek, DepartmentExpand

References

SHOWING 1-10 OF 15 REFERENCES
Adiposity and metabolic dysfunction in polycystic ovary syndrome
  • Susan Sam
  • Biology, Medicine
  • Hormone molecular biology and clinical investigation
  • 2015
TLDR
This review provides an overview of many aspects of adipose tissue function in PCOS that are abnormal, and these abnormalities likely predispose to development of insulin resistance even in the absence of obesity. Expand
Identification and expression characterization of the myostatin (MSTN) gene and association analysis with growth traits in the razor clam Sinonovacula constricta.
TLDR
Quantitative real-time PCR analysis revealed that the Sc-MSTN transcript was expressed in a wide range of tissues but appeared to exhibit the greatest level of expression in the foot, and suggested that MSTN could be selected as a candidate gene for the future molecular breeding of razor clam strains. Expand
and association analysis with growth traits in the razor clam Sinonovacula constricta
  • 2015
Local overexpression of the myostatin propeptide increases glucose transporter expression and enhances skeletal muscle glucose disposal
TLDR
Myostatin inhibition has direct effects to enhance glucose disposal in muscle beyond that expected of hypertrophy alone, and this approach may offer potential for the therapy of IR syndromes. Expand
Polycystic ovary syndrome.
TLDR
Whether insulin resistance is the causative factor in the development of PCOS remains to be ascertained and the mechanism by which insulin resistance may lead to reproductive dysfunction requires further elucidation. Expand
Polycystic ovary syndrome: a review for dermatologists: Part I. Diagnosis and manifestations.
TLDR
The definition, etiology, pathogenesis, and clinical features of PCOS are reviewed, including the hallmark features of hyperandrogenism and hyperinsulinemia. Expand
Serum Myostatin Is Reduced in Individuals with Metabolic Syndrome
TLDR
Lower serum myostatin independently associated with MetS, central obesity, low HDL-C, and high triglycerides after adjustment, and higher serumMyostatin is associated with favorable metabolic profiles. Expand
Myostatin knockout drives browning of white adipose tissue through activating the AMPK‐PGC1α‐Fndc5 pathway in muscle
TLDR
A paradigm of muscle‐fat crosstalk mediated by Fndc5, which is up‐regulated and secreted from muscle to induce beige cell markers and the browning of WAT in Mstn–/– mice is defined. Expand
The role of obesity in the development of polycystic ovary syndrome.
  • A. Motta
  • Medicine
  • Current pharmaceutical design
  • 2012
TLDR
It has been reported that, after losing as little as 5 % of initial body weight obese women with PCOS improved spontaneous ovulation rates and spontaneous pregnancy, therefore, the weight loss prior to conception improves live birth rate in obesity women with or without PCOS. Expand
Expression and function of myostatin in obesity, diabetes, and exercise adaptation.
TLDR
The purpose of this review was to summarize the work to date on the expression and function of myostatin in obesity, diabetes, and exercise adaptation. Expand
...
1
2
...