Correlation between level of heparinization and patency of the infarct-related coronary artery after treatment of acute myocardial infarction with alteplase (rt-PA).

@article{Arnout1992CorrelationBL,
  title={Correlation between level of heparinization and patency of the infarct-related coronary artery after treatment of acute myocardial infarction with alteplase (rt-PA).},
  author={J M M C Arnout and Maarten Simoons and David de Bono and Hans J. Rapold and D{\'e}sir{\'e} Collen and Marc Verstraete},
  journal={Journal of the American College of Cardiology},
  year={1992},
  volume={20 3},
  pages={513-9}
}
BACKGROUND AND OBJECTIVES The conjunctive use of intravenous heparin may influence the efficacy of alteplase for coronary thrombolysis in patients with acute myocardial infarction. In this study we examined the relation between the level of intravenous anticoagulation with heparin and sustained coronary artery patency in a subgroup of patients of the European Cooperative Study Group (ECSG) trial. METHODS In the ECSG trial, patients treated with alteplase and aspirin were randomized to… CONTINUE READING
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