Correlation between in vitro resistance to fluconazole and clinical outcome of oropharyngeal candidiasis in HIV-infected patients

@article{Quereda1996CorrelationBI,
  title={Correlation between in vitro resistance to fluconazole and clinical outcome of oropharyngeal candidiasis in HIV-infected patients},
  author={Carmen Quereda and Alicia Polanco and C. Giner and Aurora S{\'a}nchez-Sousa and Edwige Pereira and Enrique Navas and Jes{\'u}s Fort{\'u}n and Alejandro S{\'a}mano Guerrero and Fernando Baquero},
  journal={European Journal of Clinical Microbiology and Infectious Diseases},
  year={1996},
  volume={15},
  pages={30-37}
}
Fifty episodes of oropharyngeal candidiasis in HIV-infected patients were analyzed prospectively in order to evaluate the clinical response to fluconazole. The minimum inhibitory concentrations (MICs) of fluconazole for theCandida strains isolated from the pharynx were correlated with the clinical response. Treatment with fluconazole (100 mg/day) was successful in 86% of the cases. A good clinical outcome followed in 97% of the cases when a strain sensitive to fluconazole was isolated. This… CONTINUE READING
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Emergence of drug resistance in Candida species from HIV-infected patients receiving prolonged fluconazole therapy for oral candidosis

  • EM Johnson, DW Warnock, J Lucker, SR Parker, C Scully
  • Journal of Antimicrobial Chemotherapy
  • 1995
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