Correlation between genetic alterations and microscopic features, clinical manifestations, and prognostic characteristics of thyroid papillary carcinomas.

@article{Adeniran2006CorrelationBG,
  title={Correlation between genetic alterations and microscopic features, clinical manifestations, and prognostic characteristics of thyroid papillary carcinomas.},
  author={Adebowale J Adeniran and Zhaowen Zhu and Manoj Gandhi and David L Steward and James P Fidler and Thomas J. Giordano and Paul W. Biddinger and Yuri E Nikiforov},
  journal={The American journal of surgical pathology},
  year={2006},
  volume={30 2},
  pages={216-22}
}
Papillary carcinoma is the most common type of thyroid malignancy. It has been recently shown that these tumors commonly have one of three genetic alterations: BRAF point mutations, RET/PTC rearrangements, or RAS point mutations. In this study, we analyze the relationship between these alterations and the microscopic features of papillary carcinomas, their clinical features, and prognostic characteristics. Ninety-seven papillary carcinomas were studied; in all cases, frozen tissue was available… CONTINUE READING
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