Correlation between fundamental binding forces and clinical prognosis of Staphylococcus aureus infections of medical implants.

@article{Yongsunthon2007CorrelationBF,
  title={Correlation between fundamental binding forces and clinical prognosis of Staphylococcus aureus infections of medical implants.},
  author={R. Yongsunthon and V. Fowler and B. Lower and F. P. Vellano and E. Alexander and L. Reller and G. Corey and S. Lower},
  journal={Langmuir : the ACS journal of surfaces and colloids},
  year={2007},
  volume={23 5},
  pages={
          2289-92
        }
}
Atomic force microscopy was used to "fish" for binding reactions between a fibronectin-coated probe (i.e., substrate simulating an implant device) and each of 15 different isolates of Staphylococcus aureus obtained from either patients with an infected cardiac prosthesis (invasive group) or healthy human subjects (control group). There is a strong distinction (p = 0.01) in the binding-force signature observed for the invasive versus control populations. This observation suggests that a… Expand
34 Citations

Figures, Tables, and Topics from this paper

Polymorphisms in fibronectin binding protein A of Staphylococcus aureus are associated with infection of cardiovascular devices
  • 64
  • PDF
Forces driving the attachment of Staphylococcus epidermidis to fibrinogen-coated surfaces.
  • 18
Amino acid polymorphisms in the fibronectin-binding repeats of fibronectin-binding protein A affect bond strength and fibronectin conformation
  • 12
  • PDF
A tactile response in Staphylococcus aureus.
  • 17
  • PDF
...
1
2
3
4
...

References

SHOWING 1-10 OF 16 REFERENCES
Nature
  • R. Rosenfeld
  • Medicine
  • Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • 2009
  • 54,629
University of Texas Medical Branch at Galveston.
  • 470
  • PDF
Langmuir
  • Langmuir
  • 2007
AdV. Appl. Microbiol. J. Electron Spectrosc. Relat. Phenom
  • AdV. Appl. Microbiol. J. Electron Spectrosc. Relat. Phenom
  • 2006
J. Med
  • J. Med
  • 2005
J. R. Mol. Microbiol
  • J. R. Mol. Microbiol
  • 2004
N. Engl. J. Med
  • N. Engl. J. Med
  • 2004
J. Bacteriol
  • J. Bacteriol
  • 2003
Circulation Calderwood, S. B. N. Engl. J. Med
  • Circulation Calderwood, S. B. N. Engl. J. Med
  • 2001
J. Med
  • J. Med
  • 2001
...
1
2
...