Correlation between ethanol behavioral sensitization and midbrain dopamine neuron reactivity to ethanol.

@article{Didone2016CorrelationBE,
  title={Correlation between ethanol behavioral sensitization and midbrain dopamine neuron reactivity to ethanol.},
  author={Vincent Didone and S{\'e}bastien Masson and Caroline Quoilin and Vincent Seutin and Etienne Quertemont},
  journal={Addiction biology},
  year={2016},
  volume={21 2},
  pages={387-96}
}
Repeated ethanol injections lead to a sensitization of its stimulant effects in mice. Some recent results argue against a role for ventral tegmental area (VTA) dopamine neurons in ethanol behavioral sensitization. The aim of the present study was to test whether in vivo ethanol locomotor sensitization correlates with changes in either basal- or ethanol-evoked firing rates of dopamine neurons in vitro. Female Swiss mice were daily injected with 2.5 g/kg ethanol (or saline in the control group… CONTINUE READING