Correlation between decreased collagen production in diabetic animals and in cells exposed to diabetic serum: response to insulin.


Collagen production has been shown to be decreased in costal cartilage from nondiabetic animals after incubation with diabetic rat serum. Since collagen was decreased to a similar degree in tissues from diabetic animals, we questioned whether altered collagen production in vivo could be related to altered production induced in vitro. Collagen and… (More)


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