Correlation between brain-adrenal axis activation and cognitive impairment in alzheimer's disease: Is there a gender effect?

@article{Oxenkrug1989CorrelationBB,
  title={Correlation between brain-adrenal axis activation and cognitive impairment in alzheimer's disease: Is there a gender effect?},
  author={Gregory Oxenkrug and Dora B. Gurevich and Benjamin M. Siegel and Manuel S. Dumlao and Samuel Gershon},
  journal={Psychiatry Research},
  year={1989},
  volume={29},
  pages={169-175}
}
The present study evaluates the relationship between brain-adrenal axis activity and cognitive function in patients suffering from senile dementia of the Alzheimer's type (SDAT). Thirty-four subjects (20 females and 14 males) were assessed using the Global Deterioration Scale (GDS) and plasma cortisol levels after administration of 0.5 mg of dexamethasone. The results show a positive Spearman rank correlation between the GDS scores and postdexamethasone cortisol levels only in female subjects… CONTINUE READING
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