Correlation between angiotensin-converting enzyme, vascular endothelial growth factor, and matrix metalloproteinase-9 in the vitreous of eyes with diabetic retinopathy.

@article{Ishizaki2006CorrelationBA,
  title={Correlation between angiotensin-converting enzyme, vascular endothelial growth factor, and matrix metalloproteinase-9 in the vitreous of eyes with diabetic retinopathy.},
  author={Eisuke Ishizaki and Shinji Takai and Mari Ueki and Takatoshi Maeno and Midori Maruichi and Tetsuya Sugiyama and Hidehiro Oku and Tsunehiko Ikeda and Mizuo Miyazaki},
  journal={American journal of ophthalmology},
  year={2006},
  volume={141 1},
  pages={129-134}
}
PURPOSE To investigate the involvement of angiotensin-converting enzyme (ACE) with angiogenic factors, vascular endothelial growth factor (VEGF), and matrix metalloproteinase (MMP)-9 in the vitreous of eyes with proliferative diabetic retinopathy (PDR). DESIGN Observational case series. METHODS Angiotensin-converting enzyme activity in the vitreous was measured by using a synthetic substrate for ACE. VEGF and MMP-9 concentrations were determined by enzyme-linked immunosorbent assay… CONTINUE READING
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