• Biology, Medicine
  • Published in
    Analytical and quantitative…

Correlation between VEGF expression and angiogenesis in breast carcinoma.

  title={Correlation between VEGF expression and angiogenesis in breast carcinoma.},
  author={Logasundaram Rajesh and Kusum Joshi and Veena Bhalla and Pranab Dey and Bishan Das Radotra and Raje Nijhawan},
  journal={Analytical and quantitative cytology and histology},
  volume={26 2},
OBJECTIVE To analyze the role of vascular endothelial growth factor (VEGF) secreted by tumor cells in angiogenesis of breast carcinoma using image morphometry. STUDY DESIGN Thirty-four cases of node-negative breast carcinoma were used in the study. There were 6 grade 1, 20 grade 2 and 8 grade 3 tumors. For each case, 2 consecutive sections from the same block were cut. Immunostaining for VEGF and CD31 was carried out, and areas of highest staining density were marked. Those marked "hot spots… CONTINUE READING