Correlation between In Vivo Biofilm Formation and Virulence Gene Expression in Escherichia coli O104:H4

@inproceedings{Safadi2012CorrelationBI,
  title={Correlation between In Vivo Biofilm Formation and Virulence Gene Expression in Escherichia coli O104:H4},
  author={Rim Al Safadi and Galeb S. Abu-Ali and Rudolph E. Sloup and James T. Rudrik and Christopher M. Waters and Kathryn A. Eaton and Shannon D. Manning},
  booktitle={PloS one},
  year={2012}
}
The emergence of novel pathogens poses a major public health threat causing widespread epidemics in susceptible populations. The Escherichia coli O104:H4 strain implicated in a 2011 outbreak in northern Germany caused the highest frequency of hemolytic uremic syndrome (HUS) and death ever recorded in a single E. coli outbreak. Therefore, it has been suggested that this strain is more virulent than other pathogenic E. coli (e.g., E. coli O157:H7). The E. coli O104:H4 outbreak strain possesses… CONTINUE READING