Correlation between Genetic and Geographic Structure in Europe

  title={Correlation between Genetic and Geographic Structure in Europe},
  author={O. Lao and T. T. Lu and M. Nothnagel and O. Junge and S. Freitag-Wolf and A. Caliebe and Miroslava Bala{\vs}{\vc}{\'a}kov{\'a} and J. Bertranpetit and L. Bindoff and D. Comas and G. Holmlund and A. Kouvatsi and M. Macek and I. Mollet and W. Parson and J. Palo and R. Płoski and A. Sajantila and A. Tagliabracci and U. Gether and T. Werge and F. Rivadeneira and A. Hofman and A. Uitterlinden and C. Gieger and Heinz-Erich Wichmann and A. Ruether and S. Schreiber and C. Becker and P. N{\"u}rnberg and M. Nelson and M. Krawczak and M. Kayser},
  journal={Current Biology},
  • O. Lao, T. T. Lu, +30 authors M. Kayser
  • Published 2008
  • Geography, Medicine, Biology
  • Current Biology
  • Understanding the genetic structure of the European population is important, not only from a historical perspective, but also for the appropriate design and interpretation of genetic epidemiological studies. Previous population genetic analyses with autosomal markers in Europe either had a wide geographic but narrow genomic coverage [1, 2], or vice versa [3-6]. We therefore investigated Affymetrix GeneChip 500K genotype data from 2,514 individuals belonging to 23 different subpopulations… CONTINUE READING

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