Correlating antimicrobial activity and model membrane leakage induced by nylon-3 polymers and detergents.


Most antimicrobial peptides act upon target microorganisms by permeabilizing their membranes. The mode of action is often assessed by vesicle leakage experiments that use model membranes, with the assumption that biological activity correlates with the permeabilization of the lipid bilayer. The current work aims to extend the interpretation of vesicle… (More)
DOI: 10.1039/c5sm01521a


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