Correlating antimicrobial activity and model membrane leakage induced by nylon-3 polymers and detergents.

Abstract

Most antimicrobial peptides act upon target microorganisms by permeabilizing their membranes. The mode of action is often assessed by vesicle leakage experiments that use model membranes, with the assumption that biological activity correlates with the permeabilization of the lipid bilayer. The current work aims to extend the interpretation of vesicle… (More)
DOI: 10.1039/c5sm01521a

Topics

7 Figures and Tables

Slides referencing similar topics