Correlates of protective cellular immunity revealed by analysis of population-level immune escape pathways in HIV-1.

Abstract

HLA class I-associated polymorphisms identified at the population level mark viral sites under immune pressure by individual HLA alleles. As such, analysis of their distribution, frequency, location, statistical strength, sequence conservation, and other properties offers a unique perspective from which to identify correlates of protective cellular immunity… (More)
DOI: 10.1128/JVI.01998-12

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