Correlates of IL-10 and IL-12 Concentrations in Cervical Secretions

  title={Correlates of IL-10 and IL-12 Concentrations in Cervical Secretions},
  author={Patti Gravitt and Allan Hildesheim and Rolando Herrero and Mark Schiffman and Mark E. Sherman and Maria Concepcion Bratti and Ana Cecilia Rodr{\'i}guez and Lidia Ana Morera and Fernando C{\'a}rdenas and Frederick P Bowman and Keerti V. Shah and Peggy A. Crowley-Nowick},
  journal={Journal of Clinical Immunology},
Interindividual variations in host immune responses to HPV infection are thought to be important determinants of viral persistence and progression to cervical intraepithelial neoplasia and cancer. However, few studies have measured local immune markers at the site of infection (e.g., the cervical mucosa). We sought to determine biologic correlates of IL-10 and IL-12 concentrations in cervical secretions. Cervical secretions were passively collected using a WeckCel sponge from 247 women… CONTINUE READING
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