Correlates of HIV-1 Genital Shedding in Tanzanian Women

  title={Correlates of HIV-1 Genital Shedding in Tanzanian Women},
  author={Clare Tanton and Helen A Weiss and J{\'e}r{\^o}me Le Goff and John M. Changalucha and Mary Rusizoka and Kathy Baisley and Dean Everett and David Anthony Ross and Laurent B{\'e}lec and Richard J Hayes and Deborah Watson-Jones},
  booktitle={PloS one},
BACKGROUND Understanding the correlates of HIV shedding is important to inform strategies to reduce HIV infectiousness. We examined correlates of genital HIV-1 RNA in women who were seropositive for both herpes simplex virus (HSV)-2 and HIV-1 and who were enrolled in a randomised controlled trial of HSV suppressive therapy (aciclovir 400 mg b.i.d vs. placebo) in Tanzania. METHODOLOGY Samples, including a cervico-vaginal lavage, were collected and tested for genital HIV-1 and HSV and… CONTINUE READING
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