Correlated changes between regulatory cis elements and condition-specific expression in paralogous gene families

@inproceedings{Singh2010CorrelatedCB,
  title={Correlated changes between regulatory cis elements and condition-specific expression in paralogous gene families},
  author={Larry N. Singh and Sridhar Hannenhalli},
  booktitle={Nucleic acids research},
  year={2010}
}
Gene duplication is integral to evolution, providing novel opportunities for organisms to diversify in function. One fundamental pathway of functional diversification among initially redundant gene copies, or paralogs, is via alterations in their expression patterns. Although the mechanisms underlying expression divergence are not completely understood, transcription factor binding sites and nucleosome occupancy are known to play a significant role in the process. Previous attempts to detect… CONTINUE READING

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