Correlated autoradiographic and ion-microscopic study of the role of iodine in the formation of “cold” follicles in young and old mice

@article{Mestdagh1990CorrelatedAA,
  title={Correlated autoradiographic and ion-microscopic study of the role of iodine in the formation of “cold” follicles in young and old mice},
  author={Carole Mestdagh and M. Many and Sylvain Halpern and Colette Briançon and Philippe Fragu and J. Denef},
  journal={Cell and Tissue Research},
  year={1990},
  volume={260},
  pages={449-457}
}
The role of iodine in the formation of “cold” follicles (not labeled on autoradiograms after radioiodine administration) was analysed in ICR female mice during aging and involution of thyroid hyperplasia, by use of light and electron microscopy and by comparing autoradiographic and analytical ion-microscopic images for the same follicle in serial sections. The proportion of “cold” and “partly cold” (displaying a patchy or ring labeling pattern on autoradiograms) follicles increased… CONTINUE READING