Correction to: Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21WAF1/CIP1 expression

@inproceedings{Ho2015CorrectionTL,
  title={Correction to: Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21WAF1/CIP1 expression},
  author={Dong Hwan Ho and Hyejung Kim and Jisun Kim and Hyuna Sim and Hyunjun Ahn and Janghwan Kim and Hyemyung Seo and Kwang Chul Chung and Bum-Joon Park and Ilhong Son and Wongi Seol},
  booktitle={Molecular Brain},
  year={2015}
}
Leucine-rich repeat kinase 2 (LRRK2) is a gene in which a mutation causes Parkinson’s disease (PD), and p53 is a prototype tumor suppressor. In addition, activation of p53 in patient with PD has been reported by several studies. Because phosphorylation of p53 is critical for regulating its activity and LRRK2 is a kinase, we tested whether p53 is phosphorylated by LRRK2. LRRK2 phosphorylates threonine (Thr) at TXR sites in an in vitro kinase assay, and the T304 and T377 were identified as… CONTINUE READING