Correction of spillover radioactivities for estimation of the blood time-activity curve from the imaged LV chamber in cardiac dynamic FDG PET studies.

@article{Lin1995CorrectionOS,
  title={Correction of spillover radioactivities for estimation of the blood time-activity curve from the imaged LV chamber in cardiac dynamic FDG PET studies.},
  author={Kun-You Lin and Sung-cheng Huang and Younggeun Choi and Richard C. Brunken and Heinrich R. Schelbert and Michael E. Phelps},
  journal={Physics in medicine and biology},
  year={1995},
  volume={40 4},
  pages={629-42}
}
In dynamic cardiac PET FDG studies for measurement of myocardial metabolic rate of glucose (MMRGlc), the plasma FDG time-activity curve (input function) is commonly obtained from the left ventricular (LV) region on the PET images. The input function is contaminated by spillover of radioactivity from the surrounding myocardium and this could cause significant error in the estimated MMRGlc. In this study, we determined the effect of myocardial to blood pool spillover on MMRGlc and developed a… CONTINUE READING

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