Correction: Age-Related Decrease in the Mitochondrial Sirtuin Deacetylase Sirt3 Expression Associated with ROS Accumulation in the Auditory Cortex of the Mimetic Aging Rat Model

@inproceedings{Zeng2014CorrectionAD,
  title={Correction: Age-Related Decrease in the Mitochondrial Sirtuin Deacetylase Sirt3 Expression Associated with ROS Accumulation in the Auditory Cortex of the Mimetic Aging Rat Model},
  author={Lingling Zeng and Yang Yang and Yujuan Hu and Yu Sun and Zhengde Du and Zhen Xie and Tao Zhou and Wei-jia Kong},
  booktitle={PloS one},
  year={2014}
}
Age-related dysfunction of the central auditory system, also known as central presbycusis, can affect speech perception and sound localization. Understanding the pathogenesis of central presbycusis will help to develop novel approaches to prevent or treat this disease. In this study, the mechanisms of central presbycusis were investigated using a mimetic aging rat model induced by chronic injection of D-galactose (D-Gal). We showed that malondialdehyde (MDA) levels were increased and manganese… CONTINUE READING