Correcting susceptibility-induced distortion in diffusion-weighted MRI using constrained nonrigid registration

  title={Correcting susceptibility-induced distortion in diffusion-weighted MRI using constrained nonrigid registration},
  author={Chitresh Bhushan and Justin P. Haldar and Anand A. Joshi and Richard M. Leahy},
  journal={Proceedings of The 2012 Asia Pacific Signal and Information Processing Association Annual Summit and Conference},
Echo Planar Imaging (EPI) is the standard pulse sequence used in fast diffusion-weighted magnetic resonance imaging (MRI), but is sensitive to susceptibility-induced inhomogeneities in the main B0 magnetic field. In diffusion MRI of the human head, this leads to geometric distortion of the brain in reconstructed diffusion images and a resulting lack of correspondence with the high-resolution MRI scans that are used to define the subject anatomy. In this study, we propose and test an approach to… CONTINUE READING
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