Correcting positional correlations in Affymetrix® Genome Chips

Abstract

We report and model a previously undescribed systematic error causing spurious excess correlations that depend on the distance between probes on Affymetrix® microarrays. The phenomenon affects pairs of features with large chip separations, up to over 100 probes apart. The effect may have a significant impact on analysis of correlations in large collections… (More)
DOI: 10.1038/srep09078

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