Correcting positional correlations in Affymetrix® Genome Chips


We report and model a previously undescribed systematic error causing spurious excess correlations that depend on the distance between probes on Affymetrix® microarrays. The phenomenon affects pairs of features with large chip separations, up to over 100 probes apart. The effect may have a significant impact on analysis of correlations in large collections… (More)
DOI: 10.1038/srep09078

6 Figures and Tables


  • Presentations referencing similar topics