Correcting Effect of Ladasten on Variations in the Subpopulation Composition of T Lymphocytes in C57Bl/6 Mice on the Experimental Model of an Anxious-Depressive State

@article{Tallerova2014CorrectingEO,
  title={Correcting Effect of Ladasten on Variations in the Subpopulation Composition of T Lymphocytes in C57Bl/6 Mice on the Experimental Model of an Anxious-Depressive State},
  author={Anna V. Tallerova and L. P. Kovalenko and O. Kuznetsova and A. D. Durnev and Sergei B Seredenin},
  journal={Bulletin of Experimental Biology and Medicine},
  year={2014},
  volume={156},
  pages={335-337}
}
We studied the effect of Ladasten (30 mg/kg intraperitoneally for 5 days) on the subpopulation composition of T cells in immunocompetent organs of male C57Bl/6 mice during modeling of an anxious-depressive state (chronic zoosocial stress). Stress exposure of animals for 30 days was followed by a decrease in the relative weight of the thymus, increase in the weight of the spleen, reduction of the percentage of T cell populations, and shift in the CD4+/CD8+ ratio toward cytotoxic T cells… 
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