Corpus callosum and experimental stroke: studies in callosotomized rats and acallosal mice.

@article{Jin2011CorpusCA,
  title={Corpus callosum and experimental stroke: studies in callosotomized rats and acallosal mice.},
  author={Kunlin Jin and Lin Xie and Fen Sun and Xiaoou Mao and David Greenberg},
  journal={Stroke},
  year={2011},
  volume={42 9},
  pages={2584-8}
}
BACKGROUND AND PURPOSE Interhemispheric inhibition via the corpus callosum has been proposed as an exacerbating factor in outcome from stroke. METHODS We measured infarct volume and behavioral outcome after middle cerebral artery occlusion in callosotomized rats and acallosal mice. RESULTS Neither callosotomy in rats nor callosal agenesis in mice improved infarct volume or behavioral outcome after middle cerebral artery occlusion. CONCLUSIONS These findings argue against a role for… CONTINUE READING

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