Coronavirus nucleocapsid protein is an RNA chaperone.

@article{Ziga2007CoronavirusNP,
  title={Coronavirus nucleocapsid protein is an RNA chaperone.},
  author={Sonia Z{\'u}{\~n}iga and Isabel Sola and Jose Luis Moreno and Patricia Sabella and Juan Plana-Dur{\'a}n and Luis Enjuanes},
  journal={Virology},
  year={2007},
  volume={357 2},
  pages={215-27}
}
RNA chaperones are nonspecific nucleic acid binding proteins with long disordered regions that help RNA molecules to adopt its functional conformation. Coronavirus nucleoproteins (N) are nonspecific RNA-binding proteins with long disordered regions. Therefore, we investigated whether transmissible gastroenteritis coronavirus (TGEV) N protein was an RNA chaperone. Purified N protein enhanced hammerhead ribozyme self-cleavage and nucleic acids annealing, which are properties that define RNA… CONTINUE READING
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