Coronavirus Disease 2019 (COVID-19) and Immune-mediated Rheumatic Diseases. Recommendations of the Association of Rheumatologists of Russia

@article{Nasonov2021CoronavirusD2,
  title={Coronavirus Disease 2019 (COVID-19) and Immune-mediated Rheumatic Diseases. Recommendations of the Association of Rheumatologists of Russia},
  author={Evgeny L. Nasonov and A. M. Lila and Vadim I. Mazurov and B. S. Belov and Andrei E. Karateev and Tatiana V. Dubinina and O. A. Nikitinskaya and Alexander A. Baranov and Diana Abdulganieva and Sergei V. Moiseev and Alena I. Zagrebneva},
  journal={Rheumatology Science and Practice},
  year={2021}
}
In mid-2021, the SARS-CoV-2 (Severe Acute Respiratory coronavirus 2) infection, which caused the coronavirus disease (COVID-19) pandemic, affected more than 157 million people in all regions of the world and led to more than 3.2 million deaths. It is assumed that elderly age, uncontrolled inflammation, anti-inflammatory therapy, comorbid pathology, genetic and other factors can potentially lead to an increase in “sensitivity” to viral and bacterial infections, including SARS-CoV-2. The new… 
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16 Citations

16 Citations

Citation Type

Citation Type

Vaccination against SARS-CoV-2 in rheumatic diseases: Safety issues
TLDR
The frequency of exacerbation of RD after vaccination against COVID-19 seems to be quite low (5–7%) and has no significant associations with a specific vaccine or anti-rheumatic therapy, and unambiguous interpretation is difficult.
B cell depletion in immune-mediated rheumatic diseases and coronavirus disease 2019 (COVID-19)
TLDR
According to the recommendations of the Association of Rheumatologists of Russia, a more rigorous assessment of indications for induction and maintenance therapy of RTX therapy and harmonization of the timing of drug administration and vaccination is required.
Effect of COVID-19 coronavirus infection on the course of rheumatoid arthritis
TLDR
The effect of coronavirus infection on the course of rheumatoid arthritis (RA), the severity of infection, the effect of current baseline therapy on infection outcomes, and the role of vaccination against COVID-19 were assessed.
Safety of COVID-19 vaccines in patients with immunoinflammatory rheumatic diseases (preliminary data)
TLDR
Preliminary data suggest that vaccination against COVID-19 in patients with IRD appears to be quite safe, and further studies are needed to investigate the safety, immunogenicity, and clinical efficacy of CO VID-19 immunization in rheumatic patients.
Musculoskeletal manifectations of the new coronavirus infection: focus on arthralgia and myalgia
TLDR
Use of non-steroid anti-inflammatory drugs and vitamin D during COVID-19 is a safe and effective method of pain management, including myalgia and arthralgia, but in some cases pain management is necessary.
Detection of SARS-Cov-2 N-protein in Mesenchymal Cells of Umbilical Warton's Jelly in Women with COVID-19
TLDR
The results suggesting persistence of COVID-19 viral proteins in mesenchymal cells of the umbilical cord could be an important in establishing new pathogenic mechanisms for the fetal protection against viruses are suggested.
Anti-inflammatory drugs and immunogenicity of vaccines in patients with rheumatic diseases
TLDR
The latest data on the effect of various anti-rheumatic drugs on the immunogenicity of vaccines against influenza, pneumococcal and herpes virus infections, viral hepatitis B, yellow fever and COVID-19 used in rheumatological patients are presented.
Vaccination in persons with systemic lupus erythematosus: the current state of the problem
TLDR
It has been shown that the benefits of vaccination in patients with SLE significantly outweigh the risk of adverse events or exacerbations of the disease, and the problem of vaccination of such patients requires further study.
Janus kinase inhibitors in immunoinflammatory diseases: 10 years of clinical practice in rheumatology
TLDR
The current achievements, trends and recommendations regarding the use of JAK inhibitors in the treatment of IMIDs and also in the hyper-response phase of COVID-19 are reviewed.
Organ changes after SARS-CoV-2 infection in a patient with systemic sclerosis according to autopsy
The article presents a description of a clinical case with a fatal outcome due to SARS-CoV-2 coronavirus-induced bilateral viral pneumonia with areas of pneumofibrosis, complicated by acute…
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References

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  • E. Nasonov
  • Medicine, Biology
    Rheumatology Science and Practice
  • 2021
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Potential use of glucocorticoids, biologics, JAK inhibitors, etc., blocking the effects of pro-inflammatory cytokines for treatment of COVID-19 is discussed.
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