Coronary microvascular Kv1 channels as regulatory sensors of intracellular pyridine nucleotide redox potential.

Abstract

Smooth muscle voltage-gated potassium (Kv) channels are important regulators of microvascular tone and tissue perfusion. Recent studies indicate that Kv1 channels represent a key component of the physiological coupling between coronary blood flow and myocardial oxygen demand. While the mechanisms by which metabolic changes in the heart are transduced to… (More)
DOI: 10.1111/micc.12426

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