Coronary microcirculation: physiology and pharmacology.

  title={Coronary microcirculation: physiology and pharmacology.},
  author={Tatsuya Komaru and Hiroshi Kanatsuka and Kunio Shirato},
  journal={Pharmacology & therapeutics},
  volume={86 3},
Coronary microvessels play a pivotal role in determining the supply of oxygen and nutrients to the myocardium by regulating the coronary flow conductance and substance transport. Direct approaches analyzing the coronary microvessels have provided a large body of knowledge concerning the physiological and pharmacological characteristics of the coronary circulation, as has the rapid accumulation of biochemical findings about the substances that mediate vascular functions. Myogenic and flow… CONTINUE READING
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