Coronary heart disease Growth-differentiation factor-15 improves risk stratification in ST-segment elevation myocardial infarction

@inproceedings{Kempf2007CoronaryHD,
  title={Coronary heart disease Growth-differentiation factor-15 improves risk stratification in ST-segment elevation myocardial infarction},
  author={Tibor Kempf and Erik Bj{\"o}rklund and Sylvia Olofsson and Bertil Lindahl and Tim Allhoff and T Wolczanski Peter and Joern Tongers and Kai C Wollert and Lars Wallentin},
  year={2007}
}
Aims Growth-differentiation factor-15 (GDF-15) is a transforming growth factor-b-related cytokine that is induced in the heart following ischaemia–reperfusion injury. We explored the prognostic utility of GDF-15 in patients with ST-segment elevation myocardial infarction (STEMI) receiving fibrinolytic therapy. Methods and results Circulating levels of GDF-15 were determined by an immunoradiometric assay in 741 STEMI patients who were included in the Assessment of the Safety and Efficacy of a… CONTINUE READING

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