Coronary flow reserve is impaired in patients with slow coronary flow.

@article{Erdoan2007CoronaryFR,
  title={Coronary flow reserve is impaired in patients with slow coronary flow.},
  author={Doğan Erdoğan and Mustafa Caliskan and H Ibrahim Gullu and Alpay Turan Sezgin and Aylin Yildirir and Haldun Muderrisoğlu},
  journal={Atherosclerosis},
  year={2007},
  volume={191 1},
  pages={168-74}
}
BACKGROUND Slow coronary flow (SCF) in a normal coronary angiogram is a well-recognized clinical entity, but its etiopathogenesis remains unclear. However, previous studies have suggested that microvascular abnormalities and endothelial dysfunction responsible for SCF. Accordingly, we hypothesized that SCF phenomenon may be a form, at least early phase, of atherosclerosis that involve both small vessels and epicardial coronary arteries, and therefore we investigated coronary flow reserve (CFR… CONTINUE READING

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