Coronary artery spasm induced in miniature swine: angiographic evidence and relation to coronary atherosclerosis.

@article{Shimokawa1985CoronaryAS,
  title={Coronary artery spasm induced in miniature swine: angiographic evidence and relation to coronary atherosclerosis.},
  author={Hiroaki Shimokawa and Hitonobu Tomoike and S Nabeyama and H Yamamoto and Yasushi Ishii and Kenichi Tanaka and Masato Nakamura},
  journal={American heart journal},
  year={1985},
  volume={110 2},
  pages={300-10}
}
In a swine model of coronary artery spasm, the pathogenetic role of coronary atherosclerosis was examined. Following endothelial balloon denudation of the left circumflex coronary artery (LCX), male miniature swine were fed a laboratory chow diet containing 2% cholesterol. Although there was no difference in the extent of coronary vasoconstrictive response to histamine, serotonin, and ergonovine between the left anterior descending coronary artery (LAD) and the LCX before the denudation, a… CONTINUE READING

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