Coronary arterioles in type 2 diabetic (db/db) mice undergo a distinct pattern of remodeling associated with decreased vessel stiffness

@article{Katz2011CoronaryAI,
  title={Coronary arterioles in type 2 diabetic (db/db) mice undergo a distinct pattern of remodeling associated with decreased vessel stiffness},
  author={Paige S. Katz and Aaron J. Trask and Flavia M Souza-Smith and Kirk R. Hutchinson and Maarten L. Galantowicz and Kevin C. Lord and James A. Stewart and Mary J. Cismowski and Kurt J Varner and Pamela A. Lucchesi},
  journal={Basic Research in Cardiology},
  year={2011},
  volume={106},
  pages={1123-1134}
}
Little is known about the impact of type 2 diabetes mellitus (DM) on coronary arteriole remodeling. The aim of this study was to determine the mechanisms that underlie coronary arteriole structural remodeling in type 2 diabetic (db/db) mice. Passive structural properties of septal coronary arterioles isolated from 12- to 16-week-old diabetic db/db and control mice were assessed by pressure myography. Coronary arterioles from 12-week-old db/db mice were structurally similar to age-matched… CONTINUE READING