Coronary arterial smooth muscle contraction by a substance released from platelets: evidence that it is thromboxane A2.

@article{Ellis1976CoronaryAS,
  title={Coronary arterial smooth muscle contraction by a substance released from platelets: evidence that it is thromboxane A2.},
  author={Earl F. Ellis and Oswald Oelz and Lyman Jackson Roberts and N. Ann Payne and Brian Sweetman and Alan S. Nies and John A. Oates},
  journal={Science},
  year={1976},
  volume={193 4258},
  pages={1135-7}
}
When human platelets are aggregated by thrombin, material is released that rapidly contracts strips of spirally cut porcine coronary artery. Prevention of the contraction by indomethacin suggested mediation by a prostaglandin. The contraction produced by aggregating platelets was unlike those produced by prostaglandins E2, F2alpha, G2, or H2, but resembled that evoked by thromboxane A2, which is formed by platelets during aggregation. 
93 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 93 extracted citations

Similar Papers

Loading similar papers…