Coronary angiography after cardiac arrest: Rationale and design of the COACT trial.

@article{Lemkes2016CoronaryAA,
  title={Coronary angiography after cardiac arrest: Rationale and design of the COACT trial.},
  author={Jorrit S Lemkes and Gladys Nathalia Janssens and Heleen M. Oudemans-van Straaten and Paul W. G. Elbers and Nina Willemijn van der Hoeven and Jan G. P. Tijssen and Luuk C Otterspoor and Michiel D. Voskuil and Joris J. van der Heijden and Martijn Meuwissen and Tom A Rijpstra and Georgios J. Vlachojannis and Raoul M van der Vleugel and Koen Nieman and Lucia S Jewbali and Gabe B. Bleeker and R{\'e}mon Baak and Bert Beishuizen and Martin G. Stoel and Pim van der Harst and Cyril Camaro and Jos{\'e} P S Henriques and Maarten A. Vink and Marcel T.M. Gosselink and Hans A. Bosker and Harry J.G.M. Crijns and Niels van Royen},
  journal={American heart journal},
  year={2016},
  volume={180},
  pages={
          39-45
        }
}

Coronary Angiography after Cardiac Arrest without ST‐Segment Elevation

A strategy of immediate angiography was not found to be better than a strategy of delayedAngiography with respect to overall survival at 90 days among patients who had been successfully resuscitated after out‐of‐hospital cardiac arrest and had no signs of STEMI.

Coronary Angiography After Cardiac Arrest Without ST Segment Elevation: One-Year Outcomes of the COACT Randomized Clinical Trial.

In this trial of patients successfully resuscitated after out-of-hospital cardiac arrest and without signs of STEMI, a strategy of immediate angiography was not found to be superior to a strategy with respect to clinical outcomes at 1 year, andCoronary angiographic in this patient group can therefore be delayed until after neurologic recovery without affecting outcomes.

Out-of-hospital cardiac arrest: always coronary angiography?

Immediate coronary intervention in the setting of OHCA appears to be associated with better survival to discharge; the documentation of an occluded coronary artery in medium 25% of patients without signs of STEMI at ECG helps to explain why early angiography can improve outcomes.

Predictors of coronary artery disease in cardiac arrest survivors: coronary angiography for everyone? A single-center retrospective analysis

In patients with cardiac arrest, ST-segment elevation, wall motion abnormalities, left ventricular dysfunction and elevated high sensitivity troponin T were predictive of coronary artery disease, and it was not possible to establish the best cutoff for coronary angiography timing.

Coronary angiography findings in cardiac arrest patients with non-diagnostic post-resuscitation electrocardiogram: A comparison of shockable and non-shockable initial rhythms

Initial shockable group of patients had a trend towards higher incidence of acute coronary lesions and higher need of ad-hoc percutaneous intervention vs non-shockable group.

Infarct-related chronic total coronary occlusion and the risk of ventricular tachyarrhythmic events in out-of-hospital cardiac arrest survivors

In out-of-hospital cardiac arrest survivors with coronary artery disease without ST-segment elevation, an IRA-CTO was not an independent factor associated with VTEs in the 1st year after the index event.

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Experts from the EAPCI and "Stent for Life" groups reviewed existing literature and provided practical guidelines on selection of patients for immediate coronary angiography (CAG), PCI strategy, concomitant antiplatelet/anticoagulation treatment, haemodynamic support and use of therapeutic hypothermia.

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