Coronary Serum Obtained After Myocardial Infarction Induces Angiogenesis and Microvascular Obstruction Repair. Role of Hypoxia-inducible Factor-1A.

@article{RosNavarro2018CoronarySO,
  title={Coronary Serum Obtained After Myocardial Infarction Induces Angiogenesis and Microvascular Obstruction Repair. Role of Hypoxia-inducible Factor-1A.},
  author={C{\'e}sar R{\'i}os-Navarro and Luisa Hueso and Gema Mi{\~n}ana and Julio N{\'u}{\~n}ez and A Ruiz-Sauri and Mar{\'i}a Jes{\'u}s Gil Sanz and Joaqu{\'i}n C{\'a}noves and Francisco J. Chorro and Laura Piqueras and Vicente Bodi},
  journal={Revista espanola de cardiologia},
  year={2018},
  volume={71 6},
  pages={440-449}
}
INTRODUCTION AND OBJECTIVES Microvascular obstruction (MVO) exerts deleterious effects following acute myocardial infarction (AMI). We investigated coronary angiogenesis induced by coronary serum and the role of hypoxia-inducible factor-1A (HIF-1A) in MVO repair. METHODS Myocardial infarction was induced in swine by transitory 90-minute coronary occlusion. The pigs were divided into a control group and 4 AMI groups: no reperfusion, 1minute, 1 week and 1 month after reperfusion. Microvascular… CONTINUE READING