Cornuside suppresses cytokine-induced proinflammatory and adhesion molecules in the human umbilical vein endothelial cells.

@article{Kang2007CornusideSC,
  title={Cornuside suppresses cytokine-induced proinflammatory and adhesion molecules in the human umbilical vein endothelial cells.},
  author={Dae Gill Kang and Mi Kyoung Moon and An Sook Lee and Tae Oh Kwon and Jin Sook Kim and Ho Sub Lee},
  journal={Biological & pharmaceutical bulletin},
  year={2007},
  volume={30 9},
  pages={1796-9}
}
Cornuside is a bisiridoid glucoside compound isolated from the fruit of Cornus officinalis SIEB. et ZUCC. The present study was designed to examine the effects of cornuside on expression levels of cytokine-induced proinflammatory and adhesion molecules in the human umbilical vein endothelial cells (HUVECs). Cornuside treatment attenuated tumor necrosis factor-alpha (TNF-alpha)-induced nuclear factor-kappa B (NF-kappaB) p65 translocation in HUVECs. In addition, cornuside suppressed the… CONTINUE READING

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