Cornigerin, a new sesqui-lignan from the hepatoprotective fractions of Cynara cornigera L.

@article{Sohafy2016CornigerinAN,
  title={Cornigerin, a new sesqui-lignan from the hepatoprotective fractions of Cynara cornigera L.},
  author={S. M. El Sohafy and Aly M Metwally and Abdalla A Omar and Masouda E Amer and Mohamed M. Radwan and Maged. S. Abdel-Kader and Sayed A El Toumy and Mahmoud A ElSohly},
  journal={Fitoterapia},
  year={2016},
  volume={115},
  pages={101-105}
}
The ethanol extract of Cynara cornigera L. was fractionated and the fractions were subjected to hepatoprotective assays using Wistar albino rats at a dose of 500 and 250mg/kg. The liver injury was induced in rats using carbon tetrachloride. Biochemical parameters such as aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP) and total bilirubin were estimated as reflections of the liver condition, with silymarin as a positive control. Phytochemical… CONTINUE READING