Cornified cell envelope formation is distinct from apoptosis in epidermal keratinocytes.

@article{Takahashi2000CornifiedCE,
  title={Cornified cell envelope formation is distinct from apoptosis in epidermal keratinocytes.},
  author={Hidetoshi Takahashi and Noriaki Aoki and Satoshi Nakamura and Katsura Asano and Akemi Ishida-Yamamoto and Hajime Iizuka},
  journal={Journal of dermatological science},
  year={2000},
  volume={23 3},
  pages={161-9}
}
In order to maintain epidermal structural homeostasis, keratinocytes need to modulate their proliferation, differentiation, and cell death. Although terminal differentiation of keratinocytes is characterized by cornified cell envelope (CE) formation and one major mechanism of cell death is apoptosis, the precise relationship between these processes remains obscure. Using normal human cultured keratinocytes (NHK), we compared A23187-induced CE formation and ultraviolet B irradiation (UVB… CONTINUE READING
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